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The Resource Technologies to enable autonomous detection for BioWatch : ensuring timely and accurate information for public health officials : workshop summary, India Hook-Barnard, Sheena M. Posey Norris, and Joe Alper, rapporteurs ; Board on Health Sciences Policy, Board on Life Sciences, Institute of Medicine and National Research Council of the National Academies

Technologies to enable autonomous detection for BioWatch : ensuring timely and accurate information for public health officials : workshop summary, India Hook-Barnard, Sheena M. Posey Norris, and Joe Alper, rapporteurs ; Board on Health Sciences Policy, Board on Life Sciences, Institute of Medicine and National Research Council of the National Academies

Creator
Author
Contributor
Summary
The BioWatch program, funded and overseen by the Department of Homeland Security (DHS), has three main elements--sampling, analysis, and response--each coordinated by different agencies. The Environmental Protection Agency maintains the sampling component, the sensors that collect airborne particles. The Centers for Disease Control and Prevention coordinates analysis and laboratory testing of the samples, though testing is actually carried out in state and local public health laboratories. Local jurisdictions are responsible for the public health response to positive findings. The Federal Bureau of Investigation is designated as the lead agency for the law enforcement response if a bioterrorism event is detected. In 2003 DHS deployed the first generation of BioWatch air samplers. The current version of this technology, referred to as Generation 2.0, requires daily manual collection and testing of air filters from each monitor. DHS has also considered newer automated technologies (Generation 2.5 and Generation 3.0) which have the potential to produce results more quickly, at a lower cost, and for a greater number of threat agents. Technologies to Enable Autonomous Detection for BioWatch is the summary of a workshop hosted jointly by the Institute of Medicine and the National Research Council in June 2013 to explore alternative cost-effective systems that would meet the requirements for a BioWatch Generation 3.0 autonomous detection system, or autonomous detector, for aerosolized agents . The workshop discussions and presentations focused on examination of the use of four classes of technologies--nucleic acid signatures, protein signatures, genomic sequencing, and mass spectrometry--that could reach Technology Readiness Level (TRL) 6-plus in which the technology has been validated and is ready to be tested in a relevant environment over three different tiers of temporal timeframes: those technologies that could be TRL 6-plus ready as part of an integrated system by 2016, those that are likely to be ready in the period 2016 to 2020, and those are not likely to be ready until after 2020. Technologies to Enable Autonomous Detection for BioWatch discusses the history of the BioWatch program, the role of public health officials and laboratorians in the interpretation of BioWatch data and the information that is needed from a system for effective decision making, and the current state of the art of four families of technology for the BioWatch program. This report explores how the technologies discussed might be strategically combined or deployed to optimize their contributions to an effective environmental detection capability
Language
eng
Work
Publication
Extent
1 online resource (1 PDF file (xvi, 244 pages))
Note
Title from PDF title page
Contents
  • Introduction
  • Overview of the BioWatch program
  • Public health's perspective on the role of BioWatch in the decision-making process
  • Potential technologies for the BioWatch program
  • Final thoughts
  • Technology readiness levels in the Department of Defense
  • White paper 1: the BioWatch program: what information is needed to inform decision making?
  • White paper 2: nucleic-acid signatures at three levels of readiness for BioWatch
  • White paper 3: state of the art for autonomous detection systems using immunoassays and protein signatures
  • White paper 4: state of the art for autonomous detection systems using genomic sequencing
  • White paper 5: state of the art for autonomous detection systems using mass spectrometry
Isbn
9780309292528
Instance
Label
Technologies to enable autonomous detection for BioWatch : ensuring timely and accurate information for public health officials : workshop summary
Title
Technologies to enable autonomous detection for BioWatch
Title remainder
ensuring timely and accurate information for public health officials : workshop summary
Statement of responsibility
India Hook-Barnard, Sheena M. Posey Norris, and Joe Alper, rapporteurs ; Board on Health Sciences Policy, Board on Life Sciences, Institute of Medicine and National Research Council of the National Academies
Creator
Contributor
Author
Sponsoring body
Subject
Genre
Language
eng
Summary
The BioWatch program, funded and overseen by the Department of Homeland Security (DHS), has three main elements--sampling, analysis, and response--each coordinated by different agencies. The Environmental Protection Agency maintains the sampling component, the sensors that collect airborne particles. The Centers for Disease Control and Prevention coordinates analysis and laboratory testing of the samples, though testing is actually carried out in state and local public health laboratories. Local jurisdictions are responsible for the public health response to positive findings. The Federal Bureau of Investigation is designated as the lead agency for the law enforcement response if a bioterrorism event is detected. In 2003 DHS deployed the first generation of BioWatch air samplers. The current version of this technology, referred to as Generation 2.0, requires daily manual collection and testing of air filters from each monitor. DHS has also considered newer automated technologies (Generation 2.5 and Generation 3.0) which have the potential to produce results more quickly, at a lower cost, and for a greater number of threat agents. Technologies to Enable Autonomous Detection for BioWatch is the summary of a workshop hosted jointly by the Institute of Medicine and the National Research Council in June 2013 to explore alternative cost-effective systems that would meet the requirements for a BioWatch Generation 3.0 autonomous detection system, or autonomous detector, for aerosolized agents . The workshop discussions and presentations focused on examination of the use of four classes of technologies--nucleic acid signatures, protein signatures, genomic sequencing, and mass spectrometry--that could reach Technology Readiness Level (TRL) 6-plus in which the technology has been validated and is ready to be tested in a relevant environment over three different tiers of temporal timeframes: those technologies that could be TRL 6-plus ready as part of an integrated system by 2016, those that are likely to be ready in the period 2016 to 2020, and those are not likely to be ready until after 2020. Technologies to Enable Autonomous Detection for BioWatch discusses the history of the BioWatch program, the role of public health officials and laboratorians in the interpretation of BioWatch data and the information that is needed from a system for effective decision making, and the current state of the art of four families of technology for the BioWatch program. This report explores how the technologies discussed might be strategically combined or deployed to optimize their contributions to an effective environmental detection capability
Member of
Cataloging source
NLM
http://library.link/vocab/creatorName
Hook-Barnard, India
Dewey number
363.32530973
Funding information
This activity was supported by contract no. HSHQDC-12-J-00188 between the National Academy of Sciences and the Department of Homeland Security, Office of Health Affairs. The views presented in this publication do not necessarily reflect the views of the organizations or agencies that provided support for the activity.
Illustrations
illustrations
Index
no index present
LC call number
UG447.8
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • technical reports
NLM call number
WA 295
http://library.link/vocab/relatedWorkOrContributorDate
2013
http://library.link/vocab/relatedWorkOrContributorName
  • Norris, Sheena M. Posey
  • Alper, Joe
  • Institute of Medicine (U.S.)
  • National Research Council (U.S.)
  • Strategies for Cost-Effective and Flexible Biodetection Systems that Ensure Timely and Accurate Information for Public Health Officials (Workshop)
http://library.link/vocab/subjectName
  • BioWatch Program (U.S.)
  • Bioterrorism
  • Health risk assessment
  • Biosecurity
  • Environmental monitoring
  • Nucleic acids
  • Proteins
  • Genomics
  • Mass spectrometry
  • BioWatch Program (U.S.)
  • Bioterrorism
  • Biohazard Release
  • Biological Warfare Agents
  • Environmental Monitoring
  • United States
  • BioWatch Program (U.S.)
  • BUSINESS & ECONOMICS
  • SOCIAL SCIENCE
  • Biosecurity
  • Bioterrorism
  • Environmental monitoring
  • Genomics
  • Health risk assessment
  • Mass spectrometry
  • Nucleic acids
  • Proteins
  • United States
Label
Technologies to enable autonomous detection for BioWatch : ensuring timely and accurate information for public health officials : workshop summary, India Hook-Barnard, Sheena M. Posey Norris, and Joe Alper, rapporteurs ; Board on Health Sciences Policy, Board on Life Sciences, Institute of Medicine and National Research Council of the National Academies
Instantiates
Publication
Note
Title from PDF title page
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Overview of the BioWatch program -- Public health's perspective on the role of BioWatch in the decision-making process -- Potential technologies for the BioWatch program -- Final thoughts -- Technology readiness levels in the Department of Defense -- White paper 1: the BioWatch program: what information is needed to inform decision making? -- White paper 2: nucleic-acid signatures at three levels of readiness for BioWatch -- White paper 3: state of the art for autonomous detection systems using immunoassays and protein signatures -- White paper 4: state of the art for autonomous detection systems using genomic sequencing -- White paper 5: state of the art for autonomous detection systems using mass spectrometry
Control code
887396122
Dimensions
unknown
Extent
1 online resource (1 PDF file (xvi, 244 pages))
Form of item
online
Isbn
9780309292528
Lccn
2014395962
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Specific material designation
remote
System control number
(OCoLC)887396122
Label
Technologies to enable autonomous detection for BioWatch : ensuring timely and accurate information for public health officials : workshop summary, India Hook-Barnard, Sheena M. Posey Norris, and Joe Alper, rapporteurs ; Board on Health Sciences Policy, Board on Life Sciences, Institute of Medicine and National Research Council of the National Academies
Publication
Note
Title from PDF title page
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Overview of the BioWatch program -- Public health's perspective on the role of BioWatch in the decision-making process -- Potential technologies for the BioWatch program -- Final thoughts -- Technology readiness levels in the Department of Defense -- White paper 1: the BioWatch program: what information is needed to inform decision making? -- White paper 2: nucleic-acid signatures at three levels of readiness for BioWatch -- White paper 3: state of the art for autonomous detection systems using immunoassays and protein signatures -- White paper 4: state of the art for autonomous detection systems using genomic sequencing -- White paper 5: state of the art for autonomous detection systems using mass spectrometry
Control code
887396122
Dimensions
unknown
Extent
1 online resource (1 PDF file (xvi, 244 pages))
Form of item
online
Isbn
9780309292528
Lccn
2014395962
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Specific material designation
remote
System control number
(OCoLC)887396122

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