The Resource The effectiveness of procedures to remove or occlude the left atrial appendage : a systematic review of the evidence, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP), Portland VA Medical Center ; principal investigator: North Noelck, co-investigators: Joel Papak, Michele Freeman, Robin Paynter, Allison Low, Makalapua Motuapuaka, Karli Kondo, Devan Kansagara

The effectiveness of procedures to remove or occlude the left atrial appendage : a systematic review of the evidence, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP), Portland VA Medical Center ; principal investigator: North Noelck, co-investigators: Joel Papak, Michele Freeman, Robin Paynter, Allison Low, Makalapua Motuapuaka, Karli Kondo, Devan Kansagara

Label
The effectiveness of procedures to remove or occlude the left atrial appendage : a systematic review of the evidence
Title
The effectiveness of procedures to remove or occlude the left atrial appendage
Title remainder
a systematic review of the evidence
Statement of responsibility
prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP), Portland VA Medical Center ; principal investigator: North Noelck, co-investigators: Joel Papak, Michele Freeman, Robin Paynter, Allison Low, Makalapua Motuapuaka, Karli Kondo, Devan Kansagara
Title variation
QUERI
Creator
Contributor
Author
Issuing body
Sponsoring body
Subject
Genre
Language
eng
Summary
Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting between 2.7 and 6.1 million people in the United States. The prevalence of AF increases with age and is often associated with structural heart disease and co-morbidities that are common in the Veteran population. AF is the most important cause of cardioembolic stroke, which accounts for 14-36% of all ischemic strokes. While patients at highest risk for AF-related stroke also often have other independent risk factors for stroke secondary to atherosclerotic aortic or carotid disease, most cardiac sources of embolism are thought to be due to thrombus formation from blood stasis in the left atrium. Among patients with non-valvular AF more than 90% of thrombi develop in the left atrial appendage (LAA). Antithrombotic therapy with aspirin, warfarin, or one of several newer oral anticoagulants reduces the risk of stroke due to both atrial fibrillation and atherosclerotic disease but is associated with a risk of serious bleeding. As a potential alternative to long-term anticoagulant therapy, various LAA exclusion procedures have been developed in an attempt to isolate the LAA from circulating blood flow. These procedures, including both surgical occlusion and removal of the LAA and percutaneous catheter-based interventions to occlude the LAA, may be beneficial in reducing risk of cardioembolic stroke originating from the LAA. The purpose of this report is to systematically review the literature to better understand the balance of benefits and harms of surgical or percutaneous LAA exclusion procedures
Member of
Cataloging source
MMU
http://library.link/vocab/creatorName
Noelck, North
Government publication
federal national government publication
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • surveys of literature
NLM call number
WG 330.5.A5
http://library.link/vocab/relatedWorkOrContributorName
  • United States
  • Portland VA Medical Center
  • Quality Enhancement Research Initiative (U.S.)
Series statement
Evidence-based synthesis program
http://library.link/vocab/subjectName
  • Atrial Appendage
  • Atrial Fibrillation
  • Anticoagulants
  • Risk Factors
  • Comparative Effectiveness Research
  • Evidence-Based Medicine
  • Veterans
  • United States
  • United States
Label
The effectiveness of procedures to remove or occlude the left atrial appendage : a systematic review of the evidence, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP), Portland VA Medical Center ; principal investigator: North Noelck, co-investigators: Joel Papak, Michele Freeman, Robin Paynter, Allison Low, Makalapua Motuapuaka, Karli Kondo, Devan Kansagara
Instantiates
Publication
Note
  • "VA-ESP Project #05-225 "
  • "October 2015."
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
  • text
  • still image
Content type code
  • txt
  • sti
Content type MARC source
  • rdacontent
  • rdacontent
Control code
961273563
Extent
1 online resource (vi, 52 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Specific material designation
remote
System control number
(OCoLC)961273563
Label
The effectiveness of procedures to remove or occlude the left atrial appendage : a systematic review of the evidence, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP), Portland VA Medical Center ; principal investigator: North Noelck, co-investigators: Joel Papak, Michele Freeman, Robin Paynter, Allison Low, Makalapua Motuapuaka, Karli Kondo, Devan Kansagara
Publication
Note
  • "VA-ESP Project #05-225 "
  • "October 2015."
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
  • text
  • still image
Content type code
  • txt
  • sti
Content type MARC source
  • rdacontent
  • rdacontent
Control code
961273563
Extent
1 online resource (vi, 52 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations.
Specific material designation
remote
System control number
(OCoLC)961273563

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