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The Resource The epigenome and developmental origins of health and disease, edited by Cheryl S. Rosenfeld

The epigenome and developmental origins of health and disease, edited by Cheryl S. Rosenfeld

Label
The epigenome and developmental origins of health and disease
Title
The epigenome and developmental origins of health and disease
Statement of responsibility
edited by Cheryl S. Rosenfeld
Contributor
Editor
Subject
Language
eng
Summary
"The Epigenome And Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother's diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, neurobehavioral disorders, and increased risk for cancer to list but a few examples. Importantly, the common thread of how in utero and postnatal environmental changes may lead to DOHaD effects is through various epigenetic changes. The Epigenome And Developmental Origins of Health and Disease is a unique resource not only for geneticists and epigeneticists, but also for toxicologists, obestetricians, gynecologists, neurobiologists, nutritionists, physiologists, and psychologists"--Back cover
Cataloging source
BTCTA
Dewey number
599.935
Illustrations
illustrations
Index
index present
LC call number
QH491
Literary form
non fiction
Nature of contents
bibliography
NLM call number
QU 475
http://library.link/vocab/relatedWorkOrContributorName
Rosenfeld, Cheryl S.
http://library.link/vocab/subjectName
  • Human genome
  • Epigenetics
  • Medical genetics
  • Developmental biology
  • Diseases
  • Disease susceptibility
  • Developmental Biology
  • Epigenesis, Genetic
  • Disease Susceptibility
  • Embryology
  • Genome, Human
  • Prenatal Exposure Delayed Effects
Label
The epigenome and developmental origins of health and disease, edited by Cheryl S. Rosenfeld
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier.
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent.
Contents
Introduction to the concept of developmental origins of health and disease (DOHaD) -- Historical perspective of DOHaD in humans -- Overview of the periconceptional period through post-implantational embryonic development and critical windows of time -- Introduction to epigenetic mechanisms: the probable common thread for various DOHaD effects -- Introduction to fetal hormonal development and programming -- Parental nutrition and DOHaD -- Example environmental chemicals and DOHaD -- Maternal neurological disorders, stress, trauma, and DOHaD -- Cardiovascular disorders and DOHaD -- Reproductive disorders and DOHaD (I) -- Reproductive disorders and DOHaD (II) -- Immune disorders and DOHaD (I) -- Immune disorders and DOHaD (II) -- Neurobehavioral disorders and DOHaD -- Metabolic disorders and DOHaD -- Renal disorders and DOHaD -- Cancer and DOHaD -- Gastrointestinal system and DOHaD -- How the father might epigenetically program the risk for DOHaD effects in his offspring -- Linkage between in utero environmental changes and premature birth -- Sex specific DOHaD effects in humans and animal models -- Transgenerational propagation of in utero/postnatal environmental changes -- Overall resilience and ability of the conceptus to cope with in utero environmental changes -- How DOHaD effects have and should continue to guide public policy decisions and legal decisions -- Monitoring and reversing harmful DOHaD effects -- Overall resources to keep up with the rapidly advancing DOHaD field and future directions
Control code
909330145
Dimensions
24 cm
Extent
xvii, 542 pages
Isbn
9780128013830
Media category
unmediated
Media MARC source
rdamedia.
Media type code
  • n
Other physical details
illustrations (chiefly color)
System control number
(OCoLC)909330145
Label
The epigenome and developmental origins of health and disease, edited by Cheryl S. Rosenfeld
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
volume
Carrier category code
  • nc
Carrier MARC source
rdacarrier.
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent.
Contents
Introduction to the concept of developmental origins of health and disease (DOHaD) -- Historical perspective of DOHaD in humans -- Overview of the periconceptional period through post-implantational embryonic development and critical windows of time -- Introduction to epigenetic mechanisms: the probable common thread for various DOHaD effects -- Introduction to fetal hormonal development and programming -- Parental nutrition and DOHaD -- Example environmental chemicals and DOHaD -- Maternal neurological disorders, stress, trauma, and DOHaD -- Cardiovascular disorders and DOHaD -- Reproductive disorders and DOHaD (I) -- Reproductive disorders and DOHaD (II) -- Immune disorders and DOHaD (I) -- Immune disorders and DOHaD (II) -- Neurobehavioral disorders and DOHaD -- Metabolic disorders and DOHaD -- Renal disorders and DOHaD -- Cancer and DOHaD -- Gastrointestinal system and DOHaD -- How the father might epigenetically program the risk for DOHaD effects in his offspring -- Linkage between in utero environmental changes and premature birth -- Sex specific DOHaD effects in humans and animal models -- Transgenerational propagation of in utero/postnatal environmental changes -- Overall resilience and ability of the conceptus to cope with in utero environmental changes -- How DOHaD effects have and should continue to guide public policy decisions and legal decisions -- Monitoring and reversing harmful DOHaD effects -- Overall resources to keep up with the rapidly advancing DOHaD field and future directions
Control code
909330145
Dimensions
24 cm
Extent
xvii, 542 pages
Isbn
9780128013830
Media category
unmediated
Media MARC source
rdamedia.
Media type code
  • n
Other physical details
illustrations (chiefly color)
System control number
(OCoLC)909330145

Library Locations

    • J. Otto Lottes Health Sciences LibraryBorrow it
      1 Hospital Dr, Columbia, MO, 65201, US
      38.939544 -92.328377
    • Zalk Veterinary Medical LibraryBorrow it
      Veterinary Medicine West, Columbia, MO, 65211, US
      38.941099 -92.317911
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