The Resource The evaluation of a bioactive biomaterial scaffold for the tissue engineering of articular cartilage, by Prakash S. Jayabalan, (electronic resource)
The evaluation of a bioactive biomaterial scaffold for the tissue engineering of articular cartilage, by Prakash S. Jayabalan, (electronic resource)
Resource Information
The item The evaluation of a bioactive biomaterial scaffold for the tissue engineering of articular cartilage, by Prakash S. Jayabalan, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.This item is available to borrow from 2 library branches.
Resource Information
The item The evaluation of a bioactive biomaterial scaffold for the tissue engineering of articular cartilage, by Prakash S. Jayabalan, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri Libraries.
This item is available to borrow from 2 library branches.
- Summary
- Bilayered tissue-engineered osteochondral (OC) grafts require the integration of two components; a superficial layer consisting of articular cartilage cells encapsulated in a hydrated matrix and an underlying layer comprising a stiffer, porous material to provide mechanical support and integration into the subchondral bone. Bioactive glasses (BG) are bioresorbable materials that have been shown to be osteoinductive and ostoeconductive. They have been put forward as a candidate for the bone layer of tissue engineered OC grafts. This work investigates the use of this material in this application in vivo, and then further elucidates its effect in this application by optimizing its use in vitro prior to implantation. Then we examined the effect of the type of media on the resorption of the scaffold and finally investigated the temporal effects of BG 13-93 as a culture media supplement. Our work showed that BG 13-93 may not be suitable as a bone layer for OC constructs but may instead be useful as a culture media supplement for cartilage tissue engineering purposes
- Language
- eng
- Extent
- 1 online resource (xiii, 148 pages)
- Note
-
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Dissertation advisor: James L. Cook
- Vita
- "May 2011"
- Label
- The evaluation of a bioactive biomaterial scaffold for the tissue engineering of articular cartilage
- Title
- The evaluation of a bioactive biomaterial scaffold for the tissue engineering of articular cartilage
- Statement of responsibility
- by Prakash S. Jayabalan
- Subject
-
- Cartilage cells
- Chondrocytes
- Culture Media
- Culture media (Biology)
- Dissertations, Academic -- University of Missouri--Columbia -- Veterinary pathobiology area program
- Electronic books
- Electronic bookss
- Electronic dissertations
- Electronic government information -- Missouri
- Glass
- Tissue Engineering -- methods
- Bioactive compounds
- Tissue engineering -- Methodology
- Tissue scaffolds
- bioactive glass
- culture media supplement
- osteoarthritis
- osteochondral graft
- tissue engineering
- Tissue Scaffolds
- Language
- eng
- Summary
- Bilayered tissue-engineered osteochondral (OC) grafts require the integration of two components; a superficial layer consisting of articular cartilage cells encapsulated in a hydrated matrix and an underlying layer comprising a stiffer, porous material to provide mechanical support and integration into the subchondral bone. Bioactive glasses (BG) are bioresorbable materials that have been shown to be osteoinductive and ostoeconductive. They have been put forward as a candidate for the bone layer of tissue engineered OC grafts. This work investigates the use of this material in this application in vivo, and then further elucidates its effect in this application by optimizing its use in vitro prior to implantation. Then we examined the effect of the type of media on the resorption of the scaffold and finally investigated the temporal effects of BG 13-93 as a culture media supplement. Our work showed that BG 13-93 may not be suitable as a bone layer for OC constructs but may instead be useful as a culture media supplement for cartilage tissue engineering purposes
- Cataloging source
- MMU
- http://library.link/vocab/creatorDate
- 1980-
- http://library.link/vocab/creatorName
- Jayabalan, Prakash S.
- Degree
- Ph.D.
- Dissertation year
- 2011.
- Granting institution
- University of Missouri--Columbia
- Illustrations
- illustrations
- Index
- no index present
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- theses
- bibliography
- http://library.link/vocab/subjectName
-
- Tissue engineering
- Bioactive compounds
- Glass
- Tissue scaffolds
- Cartilage cells
- Culture media (Biology)
- Glass
- Tissue Engineering
- Chondrocytes
- Culture Media
- Tissue Scaffolds
- Label
- The evaluation of a bioactive biomaterial scaffold for the tissue engineering of articular cartilage, by Prakash S. Jayabalan, (electronic resource)
- Note
-
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Dissertation advisor: James L. Cook
- Vita
- "May 2011"
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier.
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent.
- Control code
- 816702915
- Extent
- 1 online resource (xiii, 148 pages)
- Form of item
- online
- Media category
- computer
- Media MARC source
- rdamedia.
- Media type code
-
- c
- Note
- MU: Access is limited to the campus of the University of Missouri-Columbia.
- Other physical details
- illustrations (some color).
- Specific material designation
- remote
- System control number
- (OCoLC)816702915
- Label
- The evaluation of a bioactive biomaterial scaffold for the tissue engineering of articular cartilage, by Prakash S. Jayabalan, (electronic resource)
- Note
-
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Dissertation advisor: James L. Cook
- Vita
- "May 2011"
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier.
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent.
- Control code
- 816702915
- Extent
- 1 online resource (xiii, 148 pages)
- Form of item
- online
- Media category
- computer
- Media MARC source
- rdamedia.
- Media type code
-
- c
- Note
- MU: Access is limited to the campus of the University of Missouri-Columbia.
- Other physical details
- illustrations (some color).
- Specific material designation
- remote
- System control number
- (OCoLC)816702915
Subject
- Cartilage cells
- Chondrocytes
- Culture Media
- Culture media (Biology)
- Dissertations, Academic -- University of Missouri--Columbia -- Veterinary pathobiology area program
- Electronic books
- Electronic bookss
- Electronic dissertations
- Electronic government information -- Missouri
- Glass
- Tissue Engineering -- methods
- Bioactive compounds
- Tissue engineering -- Methodology
- Tissue scaffolds
- bioactive glass
- culture media supplement
- osteoarthritis
- osteochondral graft
- tissue engineering
- Tissue Scaffolds
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.missouri.edu/portal/The-evaluation-of-a-bioactive-biomaterial/jkgWa4KM4uE/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.missouri.edu/portal/The-evaluation-of-a-bioactive-biomaterial/jkgWa4KM4uE/">The evaluation of a bioactive biomaterial scaffold for the tissue engineering of articular cartilage, by Prakash S. Jayabalan, (electronic resource)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.missouri.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.missouri.edu/">University of Missouri Libraries</a></span></span></span></span></div>