Mechanosensitivity in cells and tissues

Resource Information

The work Mechanosensitivity in cells and tissues represents a distinct intellectual or artistic creation found in University of Missouri Libraries. This resource is a combination of several types including: Work, Language Material, Books.

Label

Mechanosensitivity in cells and tissues

Statement of responsibility

edited by Andre Kamkin and Irina Kiseleva

Contributor

• Kamkin, A. G., (Andreĭ Glebovich)
• Kiseleva, Irina, (Irina S.)

Editor

• Kamkin, A. G., (Andreĭ Glebovich)

Subject

• Ion Channels
• Mechanoreceptors
• Mechanoreceptors
• Mechanoreceptors -- physiology
• Mechanotransduction, Cellular

Language

eng

Summary

"Mechanosensitivity, i.e. the specific response to mechanical stimulation, is common to a wide variety of cells in many different organisms ranging from bacteria to mammals. Mechanical stress can modulate physiological processes at the molecular, cellular, and systemic level. The primary target for mechanical stimulation is the plasma membrane of the cell, which can respond to variable physical stress with changes of the open probability of mechanosensitive ion channels. Thus, acting on ion channels in the plasma membrane, mechanical stress can elicit a multitude of biochemical processes - both transient and long-lasting - inside a cell. This may ultimately influence the function of tissues and organs in health and disease. Several stretch-induced signaling cascades have been described with multiple levels of crosstalk between the different pathways. Increased sensitivity of the cells to mechanical stress is found under various pathological conditions. A detailed study of the underlying mechanisms may therefore help to identify novel therapeutic targets for a future clinical use."

Cataloging source

EYM

http://bibfra.me/vocab/relation/editorfcompilation

5_roQuXvZP0

Illustrations

illustrations

Index

no index present

LC call number

QL938.M4

LC item number

(INTERNET)

Literary form

non fiction

Nature of contents

• dictionaries
• bibliography

NLM call number

WL 102.9